Ramose was a noble who served as the Mayor of Thebes during the reign of Pharaoh Amenhotep III, around the 14th century BCE. His tomb is located in the Valley of the Nobles on the west bank of the Nile near Luxor. The Valley of the Nobles is adjacent to the Valley of the Kings and the Valley of the Queens. The area contains the burial sites of many high-ranking officials, administrators, and nobles from ancient Egyptian times, spanning the Old Kingdom through the New Kingdom periods.

The tomb is renowned for its vibrant and well-preserved wall paintings, which depict scenes from Ramose's life, including his family, his role in the administration of Thebes, and various religious ceremonies. These paintings offer valuable insights into the daily life, religious beliefs, and artistic practices of ancient Egypt.

The Tomb of Ramose is notable for its architectural features, including a pillared hall and several chambers. The tomb's innermost chamber contains a burial shaft where Ramose's sarcophagus would have been placed, although it is believed that his mummy was later moved to a different location for safekeeping.